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TargetAmine oxidase [flavin-containing] A
LigandBDBM50282510
Substrate/Competitorn/a
Meas. Tech.ChEMBL_123581 (CHEMBL732301)
IC50 123±n/a nM
Citation Brühlmann, C; Ooms, F; Carrupt, PA; Testa, B; Catto, M; Leonetti, F; Altomare, C; Carotti, A Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase. J Med Chem44:3195-8 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] A
Name:Amine oxidase [flavin-containing] A
Synonyms:AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA)
Type:Enzyme
Mol. Mass.:59515.21
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:526
Sequence:
MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
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  Blast E-value cutoff:
BDBM50282510
n/a
NameBDBM50282510
Synonyms:7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one | 7-(4-chlorobenzyloxy)-3,4-dimethyl-2H-chromen-2-one | CHEMBL274030
TypeSmall organic molecule
Emp. Form.C18H15ClO3
Mol. Mass.314.763
SMILESCc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12
Structure
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