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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cathepsin K | ||
| Ligand | BDBM50426158 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_935505 (CHEMBL2319564) | ||
| IC50 | 21300±n/a nM | ||
| Citation |  Schröder, J; Klinger, A; Oellien, F; Marhöfer, RJ; Duszenko, M; Selzer, PM Docking-based virtual screening of covalently binding ligands: an orthogonal lead discovery approach. J Med Chem56:1478-90 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cathepsin K | |||
| Name: | Cathepsin K | ||
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36975.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P43235 | ||
| Residue: | 329 | ||
| Sequence: |
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| BDBM50426158 | |||
| n/a | |||
| Name | BDBM50426158 | ||
| Synonyms: | CHEMBL2316612 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H16ClNOS | ||
| Mol. Mass. | 281.801 | ||
| SMILES | Clc1ccc(SCC2N3CCC(CC3)C2=O)cc1 |(32.66,-50.27,;31.33,-49.5,;29.99,-50.27,;28.66,-49.5,;28.66,-47.96,;27.33,-47.19,;26,-47.96,;24.66,-47.19,;23.34,-47.95,;22.01,-47.19,;22.01,-45.65,;23.34,-44.87,;23.75,-45.88,;22.88,-46.7,;24.66,-45.65,;26,-44.88,;29.99,-47.19,;31.32,-47.95,)| | ||
| Structure | 
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