| Reaction Details |
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 | Report a problem with these data |
| Target | Protein tyrosine phosphatase type IVA 3 |
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| Ligand | BDBM50436447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_967878 (CHEMBL2400558) |
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| IC50 | 800±n/a nM |
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| Citation |  Min, G; Lee, SK; Kim, HN; Han, YM; Lee, RH; Jeong, DG; Han, DC; Kwon, BM Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells. Bioorg Med Chem Lett23:3769-74 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein tyrosine phosphatase type IVA 3 |
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| Name: | Protein tyrosine phosphatase type IVA 3 |
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| Synonyms: | PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 19546.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1461022 |
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| Residue: | 173 |
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| Sequence: | MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
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| BDBM50436447 |
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| n/a |
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| Name | BDBM50436447 |
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| Synonyms: | CHEMBL2397162 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17NO3S2 |
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| Mol. Mass. | 383.484 |
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| SMILES | COc1ccccc1COc1ccccc1C=CC=C1SC(S)=NC1=O |w:16.17,18.19,c:24| |
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| Structure | 
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