| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 5 |
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| Ligand | BDBM50441864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_986898 (CHEMBL2438762) |
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| IC50 | 61000±n/a nM |
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| Citation |  Arnatt, CK; Zaidi, SA; Zhang, Z; Li, G; Richardson, AC; Ware, JL; Zhang, Y Design, syntheses, and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents. Eur J Med Chem69:647-58 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 5 |
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| Name: | C-C chemokine receptor type 5 |
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| Synonyms: | C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40540.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51681 |
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| Residue: | 352 |
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| Sequence: | MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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| BDBM50441864 |
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| n/a |
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| Name | BDBM50441864 |
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| Synonyms: | CHEMBL2436715 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H39N5O2 |
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| Mol. Mass. | 501.663 |
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| SMILES | CCN(CC)c1ccc(CN2CCC(CC2)c2ccc(OC(C)C)c(NC(=O)c3cnccn3)c2)cc1 |
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| Structure | 
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