| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 4 |
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| Ligand | BDBM50442557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_990501 (CHEMBL2446798) |
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| Ki | 470±n/a nM |
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| Citation |  Keller, M; Kaske, M; Holzammer, T; Bernhardt, G; Buschauer, A Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorg Med Chem21:6303-22 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 4 |
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| Name: | Neuropeptide Y receptor type 4 |
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| Synonyms: | NPY-Y4 | NPY4-R | NPY4R | NPY4R_HUMAN | PP1 | PPYR1 | Pancreatic polypeptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42207.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y4 PPYR1 HUMAN::P50391 |
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| Residue: | 375 |
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| Sequence: | MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNL
CLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFI
QCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSIL
ENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRR
LQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHG
NLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTE
VSKGSLRLSGRSNPI
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| BDBM50442557 |
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| n/a |
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| Name | BDBM50442557 |
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| Synonyms: | CHEMBL2440927 |
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| Type | Small organic molecule |
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| Emp. Form. | C82H112N18O16 |
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| Mol. Mass. | 1605.8777 |
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| SMILES | NCCN(CCNC(=O)CCC(=O)NCCOCCOCCNC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1)CCNC(=O)CCC(=O)NCCOCCOCCNC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r,w:28.28,84.87| |
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| Structure | 
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