| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50019083 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1361426 (CHEMBL3294050) |
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| EC50 | 3.5±n/a nM |
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| Citation |  Takano, R; Yoshida, M; Inoue, M; Honda, T; Nakashima, R; Matsumoto, K; Yano, T; Ogata, T; Watanabe, N; Toda, N Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists. Bioorg Med Chem Lett24:2949-53 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50019083 |
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| n/a |
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| Name | BDBM50019083 |
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| Synonyms: | CHEMBL3288344 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23NO3 |
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| Mol. Mass. | 361.4336 |
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| SMILES | Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(O)=O)cn2)c1 |
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| Structure | 
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