| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50038004 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1439621 (CHEMBL3383139) |
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| Ki | 193±n/a nM |
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| Citation |  Giovannoni, MP; Ciciani, G; Cilibrizzi, A; Crocetti, L; Daniele, S; Di Cesare Mannelli, L; Ghelardini, C; Giacomelli, C; Guerrini, G; Martini, C; Trincavelli, ML; Vergelli, C Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. Eur J Med Chem89:32-41 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50038004 |
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| n/a |
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| Name | BDBM50038004 |
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| Synonyms: | CHEMBL3359412 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21N5O |
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| Mol. Mass. | 407.4671 |
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| SMILES | O=c1n(Cc2ccccc2)nc(C2CCC2)c2c3cc(nn3cnc12)-c1ccccc1 |
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| Structure | 
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