| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50035218 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1457783 (CHEMBL3369800) |
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| IC50 | 830±n/a nM |
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| Citation |  Kamal, A; Srinivasa Reddy, T; Polepalli, S; Shalini, N; Reddy, VG; Subba Rao, AV; Jain, N; Shankaraiah, N Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors. Bioorg Med Chem22:5466-75 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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| BDBM50035218 |
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| n/a |
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| Name | BDBM50035218 |
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| Synonyms: | CHEMBL61 | PODOFILOX | Podophyllinic acid lactone | Podophyllotoxin (PTOX) | podophyllotoxin |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22O8 |
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| Mol. Mass. | 414.4053 |
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| SMILES | COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12 |r| |
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| Structure | 
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