| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50062558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1462900 (CHEMBL3399840) |
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| Ki | >2000±n/a nM |
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| Citation |  Zampieri, D; Laurini, E; Vio, L; Fermeglia, M; Pricl, S; Wünsch, B; Schepmann, D; Mamolo, MG Improving selectivity preserving affinity: new piperidine-4-carboxamide derivatives as effective sigma-1-ligands. Eur J Med Chem90:797-808 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50062558 |
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| n/a |
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| Name | BDBM50062558 |
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| Synonyms: | CHEMBL3397620 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22Cl2N2O |
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| Mol. Mass. | 329.265 |
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| SMILES | CC(C)NC(=O)C1CCN(Cc2ccc(Cl)cc2Cl)CC1 |
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| Structure | 
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