Compile Data Set for Download or QSAR

Found 220 hits with Last Name = 'fermeglia' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES CC(CN1C[C@H](C)O[C@H](C)C1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248926 (3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...) Show SMILES Clc1ccc(CN2CCC(Cn3c4ccccc4oc3=O)CC2)cc1 Show InChI InChI=1S/C20H21ClN2O2/c21-17-7-5-15(6-8-17)13-22-11-9-16(10-12-22)14-23-18-3-1-2-4-19(18)25-20(23)24/h1-8,16H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248926 (3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...) Show SMILES Clc1ccc(CN2CCC(Cn3c4ccccc4oc3=O)CC2)cc1 Show InChI InChI=1S/C20H21ClN2O2/c21-17-7-5-15(6-8-17)13-22-11-9-16(10-12-22)14-23-18-3-1-2-4-19(18)25-20(23)24/h1-8,16H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181060 (CHEMBL3817940) Show SMILES [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1cccc3ccccc13)N(CC1CCCCC1)C2 |r,THB:4:3:20.28:7.8| Show InChI InChI=1S/C24H32N2O/c27-24-13-21-16-26(14-18-7-2-1-3-8-18)23(24)17-25(21)15-20-11-6-10-19-9-4-5-12-22(19)20/h4-6,9-12,18,21,23-24,27H,1-3,7-8,13-17H2/t21-,23+,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50047016 (1-(4-Fluoro-phenyl)-4-[4-hydroxy-4-(3-trifluoromet...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H23F4NO2/c23-19-8-6-16(7-9-19)20(28)5-2-12-27-13-10-21(29,11-14-27)17-3-1-4-18(15-17)22(24,25)26/h1,3-4,6-9,15,29H,2,5,10-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193455 (CHEMBL3966143) Show SMILES CN(CCCCN1C(COC1=O)c1ccccc1)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C21H25ClN2O2/c1-23(15-17-9-11-19(22)12-10-17)13-5-6-14-24-20(16-26-21(24)25)18-7-3-2-4-8-18/h2-4,7-12,20H,5-6,13-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181054 (CHEMBL3819146) Show SMILES [H][C@]12CN(CC3CCCCC3)[C@]([H])(CN1Cc1ccccc1)[C@H](O)CC2 |r,TLB:15:14:3.2:22.25.24,23:22:3.2:13.14,4:3:13.14:22.25.24| Show InChI InChI=1S/C21H32N2O/c24-21-12-11-19-15-23(14-18-9-5-2-6-10-18)20(21)16-22(19)13-17-7-3-1-4-8-17/h1,3-4,7-8,18-21,24H,2,5-6,9-16H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181297 (CHEMBL3819489) Show SMILES [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50380360 (CHEMBL2017957) Show SMILES CC(=O)N(CC1CCN(Cc2ccc(Cl)cc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C22H27ClN2O/c1-18(26)25(16-19-5-3-2-4-6-19)17-21-11-13-24(14-12-21)15-20-7-9-22(23)10-8-20/h2-10,21H,11-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181054 (CHEMBL3819146) Show SMILES [H][C@]12CN(CC3CCCCC3)[C@]([H])(CN1Cc1ccccc1)[C@H](O)CC2 |r,TLB:15:14:3.2:22.25.24,23:22:3.2:13.14,4:3:13.14:22.25.24| Show InChI InChI=1S/C21H32N2O/c24-21-12-11-19-15-23(14-18-9-5-2-6-10-18)20(21)16-22(19)13-17-7-3-1-4-8-17/h1,3-4,7-8,18-21,24H,2,5-6,9-16H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181300 (CHEMBL3819437) Show SMILES [H][C@@]12C[C@@H](O)[C@@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295408 (3-[4-(N-Benzyl-N-methylamino)butyl]benzo[d]oxazol-...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccccc1 Show InChI InChI=1S/C19H22N2O2/c1-20(15-16-9-3-2-4-10-16)13-7-8-14-21-17-11-5-6-12-18(17)23-19(21)22/h2-6,9-12H,7-8,13-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295408 (3-[4-(N-Benzyl-N-methylamino)butyl]benzo[d]oxazol-...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccccc1 Show InChI InChI=1S/C19H22N2O2/c1-20(15-16-9-3-2-4-10-16)13-7-8-14-21-17-11-5-6-12-18(17)23-19(21)22/h2-6,9-12H,7-8,13-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193445 (CHEMBL3964384) Show SMILES CN(CCCCN1C(COC1=O)c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C21H26N2O2/c1-22(16-18-10-4-2-5-11-18)14-8-9-15-23-20(17-25-21(23)24)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181299 (CHEMBL3819331) Show SMILES [H][C@]12C[C@@H](O)[C@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193443 (CHEMBL3954990) Show SMILES CN(CCCCN1[C@@H](COC1=O)c1ccccc1)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H25ClN2O2/c1-23(15-17-9-11-19(22)12-10-17)13-5-6-14-24-20(16-26-21(24)25)18-7-3-2-4-8-18/h2-4,7-12,20H,5-6,13-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248955 (3-((1-(4-methylbenzyl)piperidin-4-yl)methyl)benzo[...) Show SMILES Cc1ccc(CN2CCC(Cn3c4ccccc4oc3=O)CC2)cc1 Show InChI InChI=1S/C21H24N2O2/c1-16-6-8-17(9-7-16)14-22-12-10-18(11-13-22)15-23-19-4-2-3-5-20(19)25-21(23)24/h2-9,18H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181301 (CHEMBL3819395) Show SMILES [H][C@@]12C[C@H](O)[C@@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248905 (3-((1-benzylpiperidin-4-yl)methyl)benzo[d]oxazol-2...) Show SMILES O=c1oc2ccccc2n1CC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22N2O2/c23-20-22(18-8-4-5-9-19(18)24-20)15-17-10-12-21(13-11-17)14-16-6-2-1-3-7-16/h1-9,17H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248905 (3-((1-benzylpiperidin-4-yl)methyl)benzo[d]oxazol-2...) Show SMILES O=c1oc2ccccc2n1CC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22N2O2/c23-20-22(18-8-4-5-9-19(18)24-20)15-17-10-12-21(13-11-17)14-16-6-2-1-3-7-16/h1-9,17H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50062556 (CHEMBL3397622) Show SMILES Clc1ccc(CN2CCC(CC2)C(=O)N2CCCc3ccccc23)cc1 Show InChI InChI=1S/C22H25ClN2O/c23-20-9-7-17(8-10-20)16-24-14-11-19(12-15-24)22(26)25-13-3-5-18-4-1-2-6-21(18)25/h1-2,4,6-10,19H,3,5,11-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50062557 (CHEMBL3397621) Show SMILES O=C(C1CCN(Cc2ccccc2)CC1)N1CCCc2ccccc12 Show InChI InChI=1S/C22H26N2O/c25-22(24-14-6-10-19-9-4-5-11-21(19)24)20-12-15-23(16-13-20)17-18-7-2-1-3-8-18/h1-5,7-9,11,20H,6,10,12-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181301 (CHEMBL3819395) Show SMILES [H][C@@]12C[C@H](O)[C@@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193441 (CHEMBL3955644) Show SMILES CN(CCCCN1C(=O)CSc2ccccc12)Cc1ccccc1 Show InChI InChI=1S/C20H24N2OS/c1-21(15-17-9-3-2-4-10-17)13-7-8-14-22-18-11-5-6-12-19(18)24-16-20(22)23/h2-6,9-12H,7-8,13-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193437 (CHEMBL3975617) Show SMILES CN(CCCCn1nc(oc1=O)-c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C20H23N3O2/c1-22(16-17-10-4-2-5-11-17)14-8-9-15-23-20(24)25-19(21-23)18-12-6-3-7-13-18/h2-7,10-13H,8-9,14-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50001028 ((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...) Show SMILES [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181297 (CHEMBL3819489) Show SMILES [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181055 (CHEMBL3819463) Show SMILES [H][C@]12CN(CC3CCCCC3)[C@]([H])(CN1Cc1ccccc1)[C@@H](O)CC2 |r,TLB:15:14:3.2:22.25.24,23:22:3.2:13.14,4:3:13.14:22.25.24| Show InChI InChI=1S/C21H32N2O/c24-21-12-11-19-15-23(14-18-9-5-2-6-10-18)20(21)16-22(19)13-17-7-3-1-4-8-17/h1,3-4,7-8,18-21,24H,2,5-6,9-16H2/t19-,20+,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181060 (CHEMBL3817940) Show SMILES [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1cccc3ccccc13)N(CC1CCCCC1)C2 |r,THB:4:3:20.28:7.8| Show InChI InChI=1S/C24H32N2O/c27-24-13-21-16-26(14-18-7-2-1-3-8-18)23(24)17-25(21)15-20-11-6-10-19-9-4-5-12-22(19)20/h4-6,9-12,18,21,23-24,27H,1-3,7-8,13-17H2/t21-,23+,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181055 (CHEMBL3819463) Show SMILES [H][C@]12CN(CC3CCCCC3)[C@]([H])(CN1Cc1ccccc1)[C@@H](O)CC2 |r,TLB:15:14:3.2:22.25.24,23:22:3.2:13.14,4:3:13.14:22.25.24| Show InChI InChI=1S/C21H32N2O/c24-21-12-11-19-15-23(14-18-9-5-2-6-10-18)20(21)16-22(19)13-17-7-3-1-4-8-17/h1,3-4,7-8,18-21,24H,2,5-6,9-16H2/t19-,20+,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181300 (CHEMBL3819437) Show SMILES [H][C@@]12C[C@@H](O)[C@@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| Show InChI InChI=1S/C20H30N2O/c23-20-11-18-14-22(13-17-9-5-2-6-10-17)19(20)15-21(18)12-16-7-3-1-4-8-16/h1,3-4,7-8,17-20,23H,2,5-6,9-15H2/t18-,19+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295411 (3-[4-[N-(4-Chlorobenzyl)-N-methylamino]butyl]benzo...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2/c1-21(14-15-8-10-16(20)11-9-15)12-4-5-13-22-17-6-2-3-7-18(17)24-19(22)23/h2-3,6-11H,4-5,12-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting				ACS Med Chem Lett 2: 834-839 (2011) Article DOI: 10.1021/ml2001505 BindingDB Entry DOI: 10.7270/Q2RR208C
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181113 (CHEMBL3818112) Show SMILES [H][C@@]12C[C@@H](O)[C@@]([H])(CN1Cc1cccc3ccccc13)N(CC1CCCCC1)C2 |r,THB:4:3:20.28:7.8| Show InChI InChI=1S/C24H32N2O/c27-24-13-21-16-26(14-18-7-2-1-3-8-18)23(24)17-25(21)15-20-11-6-10-19-9-4-5-12-22(19)20/h4-6,9-12,18,21,23-24,27H,1-3,7-8,13-17H2/t21-,23+,24+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50295411 (3-[4-[N-(4-Chlorobenzyl)-N-methylamino]butyl]benzo...) Show SMILES CN(CCCCn1c2ccccc2oc1=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2/c1-21(14-15-8-10-16(20)11-9-15)12-4-5-13-22-17-6-2-3-7-18(17)24-19(22)23/h2-3,6-11H,4-5,12-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation counting				J Med Chem 52: 5380-93 (2009) Article DOI: 10.1021/jm900366z BindingDB Entry DOI: 10.7270/Q2ZP4712
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50181113 (CHEMBL3818112) Show SMILES [H][C@@]12C[C@@H](O)[C@@]([H])(CN1Cc1cccc3ccccc13)N(CC1CCCCC1)C2 |r,THB:4:3:20.28:7.8| Show InChI InChI=1S/C24H32N2O/c27-24-13-21-16-26(14-18-7-2-1-3-8-18)23(24)17-25(21)15-20-11-6-10-19-9-4-5-12-22(19)20/h4-6,9-12,18,21,23-24,27H,1-3,7-8,13-17H2/t21-,23+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in human RPMI8226 cell membranes				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50062565 (CHEMBL3397613) Show SMILES Clc1ccc(CN2CCC(CC2)C(=O)NC2CCCCC2)cc1 Show InChI InChI=1S/C19H27ClN2O/c20-17-8-6-15(7-9-17)14-22-12-10-16(11-13-22)19(23)21-18-4-2-1-3-5-18/h6-9,16,18H,1-5,10-14H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193444 (CHEMBL3894798) Show SMILES CN(CCCCN1[C@@H](COC1=O)c1ccccc1)Cc1ccccc1 |r| Show InChI InChI=1S/C21H26N2O2/c1-22(16-18-10-4-2-5-11-18)14-8-9-15-23-20(17-25-21(23)24)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181130 (CHEMBL3818532) Show SMILES [H][C@@]12C[C@H](O)[C@@]([H])(CN1Cc1cccc3ccccc13)N(CC1CCCCC1)C2 |r,THB:4:3:20.28:7.8| Show InChI InChI=1S/C24H32N2O/c27-24-13-21-16-26(14-18-7-2-1-3-8-18)23(24)17-25(21)15-20-11-6-10-19-9-4-5-12-22(19)20/h4-6,9-12,18,21,23-24,27H,1-3,7-8,13-17H2/t21-,23+,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50062553 (CHEMBL3397625) Show SMILES Clc1ccc(CN2CCC(CC2)C(=O)N2CCc3ccccc3C2)cc1 Show InChI InChI=1S/C22H25ClN2O/c23-21-7-5-17(6-8-21)15-24-12-9-19(10-13-24)22(26)25-14-11-18-3-1-2-4-20(18)16-25/h1-8,19H,9-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181059 (CHEMBL3819588) Show SMILES [H][C@@]12C[C@H](O)[C@@]([H])(CN1Cc1ccc(cc1)-c1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:22.30:7.8| Show InChI InChI=1S/C26H34N2O/c29-26-15-24-18-28(17-20-7-3-1-4-8-20)25(26)19-27(24)16-21-11-13-23(14-12-21)22-9-5-2-6-10-22/h2,5-6,9-14,20,24-26,29H,1,3-4,7-8,15-19H2/t24-,25+,26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50062554 (CHEMBL3397624) Show SMILES O=C(C1CCN(Cc2ccccc2)CC1)N1CCc2ccccc2C1 Show InChI InChI=1S/C22H26N2O/c25-22(24-15-12-19-8-4-5-9-21(19)17-24)20-10-13-23(14-11-20)16-18-6-2-1-3-7-18/h1-9,20H,10-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain cortex sigma1 receptor by scintillation analyzer				Eur J Med Chem 90: 797-808 (2015) Article DOI: 10.1016/j.ejmech.2014.12.018 BindingDB Entry DOI: 10.7270/Q2K64KQX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193450 (CHEMBL3966773) Show SMILES CN(CCCCN1c2ccccc2CCCC1=O)Cc1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-23(18-19-10-3-2-4-11-19)16-7-8-17-24-21-14-6-5-12-20(21)13-9-15-22(24)25/h2-6,10-12,14H,7-9,13,15-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50193436 (CHEMBL3946295) Show SMILES CN(CCCCN1[C@H](COC1=O)c1ccccc1)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H25ClN2O2/c1-23(15-17-9-11-19(22)12-10-17)13-5-6-14-24-20(16-26-21(24)25)18-7-3-2-4-8-18/h2-4,7-12,20H,5-6,13-16H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting method				Eur J Med Chem 121: 712-726 (2016) Article DOI: 10.1016/j.ejmech.2016.06.001 BindingDB Entry DOI: 10.7270/Q2222WR9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181056 (CHEMBL3818546) Show SMILES [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1ccc(cc1)-c1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:22.30:7.8| Show InChI InChI=1S/C26H34N2O/c29-26-15-24-18-28(17-20-7-3-1-4-8-20)25(26)19-27(24)16-21-11-13-23(14-12-21)22-9-5-2-6-10-22/h2,5-6,9-14,20,24-26,29H,1,3-4,7-8,15-19H2/t24-,25+,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50181057 (CHEMBL3819457) Show SMILES [H][C@]12C[C@@H](O)[C@]([H])(CN1Cc1ccc(cc1)-c1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:22.30:7.8| Show InChI InChI=1S/C26H34N2O/c29-26-15-24-18-28(17-20-7-3-1-4-8-20)25(26)19-27(24)16-21-11-13-23(14-12-21)22-9-5-2-6-10-22/h2,5-6,9-14,20,24-26,29H,1,3-4,7-8,15-19H2/t24-,25+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis				J Med Chem 59: 5505-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00585 BindingDB Entry DOI: 10.7270/Q2CC12KN
					More data for this Ligand-Target Pair

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