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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50193455
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1615946 (CHEMBL3858015)
Ki 0.950000±n/a nM
Citation Zampieri, DVio, LFermeglia, MPricl, SWünsch, BSchepmann, DRomano, MMamolo, MGLaurini, E Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands. Eur J Med Chem121:712-726 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50193455
n/a
NameBDBM50193455
Synonyms:CHEMBL3966143
TypeSmall organic molecule
Emp. Form.C21H25ClN2O2
Mol. Mass.372.888
SMILESCN(CCCCN1C(COC1=O)c1ccccc1)Cc1ccc(Cl)cc1
Structure
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