| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 4-kinase type 2-alpha |
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| Ligand | BDBM50087061 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1477992 (CHEMBL3429700) |
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| IC50 | >100000±n/a nM |
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| Citation |  Mejdrová, I; Chalupská, D; Kögler, M; ?ála, M; Placková, P; Baumlová, A; Hrebabecký, H; Procházková, E; Dejmek, M; Guillon, R; Strunin, D; Weber, J; Lee, G; Birkus, G; Mertlíková-Kaiserová, H; Boura, E; Nencka, R Highly Selective Phosphatidylinositol 4-Kinase IIIß Inhibitors and Structural Insight into Their Mode of Action. J Med Chem58:3767-93 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylinositol 4-kinase type 2-alpha |
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| Name: | Phosphatidylinositol 4-kinase type 2-alpha |
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| Synonyms: | P4K2A_HUMAN | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | Phosphatidylinositol 4-kinase type II-alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54030.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104812 |
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| Residue: | 479 |
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| Sequence: | MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQP
LLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELA
IERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFG
RDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEK
VPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVL
DYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWR
AYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQI
AVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
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| BDBM50087061 |
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| n/a |
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| Name | BDBM50087061 |
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| Synonyms: | CHEMBL3426598 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N5O3 |
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| Mol. Mass. | 397.4708 |
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| SMILES | COc1ccc(cc1OC)-c1c(C)nc2c(NCCN3CCOCC3)ccnn12 |
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| Structure | 
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