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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein phosphatase non-receptor type 1 | ||
| Ligand | BDBM50093525 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1501266 (CHEMBL3587908) | ||
| IC50 | 5400±n/a nM | ||
| Citation |  Nguyen, PH; Ji, DJ; Han, YR; Choi, JS; Rhyu, DY; Min, BS; Woo, MH Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects. Bioorg Med Chem23:3730-7 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein phosphatase non-receptor type 1 | |||
| Name: | Tyrosine-protein phosphatase non-receptor type 1 | ||
| Synonyms: | PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B) | Protein tyrosine phosphatase-1B (PTP1B) | Protein-tyrosine phosphatase 1B | Protein-tyrosine phosphatase 1B (PTP1B) | Tyrosine-protein phosphatase non-receptor type 1 | Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) | ||
| Type: | Protein phosphatase | ||
| Mol. Mass.: | 49963.76 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human recombinant GST-fusion PTP1B (1-435). | ||
| Residue: | 435 | ||
| Sequence: |
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| BDBM50093525 | |||
| n/a | |||
| Name | BDBM50093525 | ||
| Synonyms: | taiwaniaflavone | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H18O10 | ||
| Mol. Mass. | 538.4579 | ||
| SMILES | Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1-c1cc(ccc1O)-c1cc(=O)c2c(O)cc(O)cc2o1 |(2.2,-12.35,;.87,-13.13,;.88,-14.67,;-.45,-15.44,;-1.79,-14.67,;-1.8,-13.14,;-.47,-12.36,;-3.12,-15.45,;-4.47,-14.67,;-5.81,-15.46,;-7.15,-14.7,;-8.47,-15.47,;-9.81,-14.7,;-8.48,-17.01,;-7.14,-17.78,;-7.15,-19.32,;-5.8,-17.02,;-4.46,-17.78,;-4.45,-19.32,;-3.11,-17,;-1.78,-17.77,;-.46,-17,;.88,-17.76,;.89,-19.3,;-.45,-20.08,;-1.78,-19.31,;-3.11,-20.08,;2.21,-16.98,;2.19,-15.44,;3.52,-14.67,;3.52,-13.13,;4.86,-15.43,;6.18,-14.67,;6.17,-13.13,;7.51,-15.42,;7.52,-16.96,;8.86,-17.73,;6.19,-17.73,;4.86,-16.97,;3.54,-17.75,)| | ||
| Structure | 
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