| Reaction Details |
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 | Report a problem with these data |
| Target | Inhibin beta A chain |
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| Ligand | BDBM50095122 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1503623 (CHEMBL3591943) |
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| IC50 | 3670±n/a nM |
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| Citation |  Zhu, J; Mishra, RK; Schiltz, GE; Makanji, Y; Scheidt, KA; Mazar, AP; Woodruff, TK Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem58:5637-48 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inhibin beta A chain |
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| Name: | Inhibin beta A chain |
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| Synonyms: | Activin beta-A chain | INHBA_MOUSE | Inhba | Inhibin beta A chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47403.32 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_109823 |
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| Residue: | 424 |
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| Sequence: | MPLLWLRGFLLASCWIIVRSSPTPGSEGHGSAPDCPSCALATLPKDGPNSQPEMVEAVKK
HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
HPQGSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDV
RIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSED
HPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTS
GSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEE
CGCS
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| BDBM50095122 |
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| n/a |
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| Name | BDBM50095122 |
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| Synonyms: | CHEMBL3589518 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N5O3 |
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| Mol. Mass. | 443.4977 |
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| SMILES | CCn1c(nc2cc(NC(=O)COC)cc(C(=O)NCc3ccccc3)c12)-c1cccnc1 |
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| Structure | 
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