| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2A13 |
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| Ligand | BDBM50008072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1486539 (CHEMBL3532208) |
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| Ki | 1400±n/a nM |
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| Citation |  Stephens, ES; Walsh, AA; Scott, EE Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes. Drug Metab Dispos40:1797-802 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2A13 |
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| Name: | Cytochrome P450 2A13 |
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| Synonyms: | CP2AD_HUMAN | CYP2A13 | CYPIIA13 | Cytochrome P450 2A13 (CYP2A13) |
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| Type: | Protein |
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| Mol. Mass.: | 56702.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16696 |
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| Residue: | 494 |
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| Sequence: | MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSN
GERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSN
VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKE
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFF
AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ
RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKK
GQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR
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| BDBM50008072 |
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| n/a |
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| Name | BDBM50008072 |
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| Synonyms: | (+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one | (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone | (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone | CHEMBL550 | ISOPTO CARPINE | PILOCARPINE | PILOCARPINE HYDROCHLORIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N2O2 |
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| Mol. Mass. | 208.2569 |
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| SMILES | CC[C@H]1[C@@H](Cc2cncn2C)COC1=O |r| |
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| Structure | 
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