| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50102027 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1446415 (CHEMBL3375529) |
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| Ki | 3320±n/a nM |
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| Citation |  Hammami, S; Mighri, Z; Dooley, CT; Nefzi, A Synthesis and analgesic activity of alkylated, reduced and constrained oligoheterocyclic peptidomimetic analogs of Leu-enkephalin. Bioorg Med Chem Lett24:4482-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50102027 |
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| n/a |
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| Name | BDBM50102027 |
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| Synonyms: | CHEMBL3326767 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H51N5OS |
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| Mol. Mass. | 565.856 |
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| SMILES | CC(C)C[C@H]1CNC(=S)N1C[C@H](Cc1ccccc1)N(C)C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N(C)C |r| |
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| Structure | 
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