| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50124135 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1520148 (CHEMBL3625720) |
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| EC50 | 0.340000±n/a nM |
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| Citation |  Fanelli, R; Besserer-Offroy, É; René, A; Côté, J; Tétreault, P; Collerette-Tremblay, J; Longpré, JM; Leduc, R; Martinez, J; Sarret, P; Cavelier, F Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. J Med Chem58:7785-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46278.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453811 |
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| Residue: | 418 |
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| Sequence: | MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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| BDBM50124135 |
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| n/a |
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| Name | BDBM50124135 |
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| Synonyms: | CHEMBL3622803 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H68N8O8Si2 |
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| Mol. Mass. | 821.1663 |
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| SMILES | C[Si](C)(C)C[C@H](NC(=O)[C@H](C[Si](C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(O)=O |r| |
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| Structure | 
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