| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50124146 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1520149 (CHEMBL3625721) |
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| EC50 | >10000±n/a nM |
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| Citation |  Fanelli, R; Besserer-Offroy, É; René, A; Côté, J; Tétreault, P; Collerette-Tremblay, J; Longpré, JM; Leduc, R; Martinez, J; Sarret, P; Cavelier, F Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. J Med Chem58:7785-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47070.64 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1466612 |
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| Residue: | 424 |
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| Sequence: | MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTD
IYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLA
MPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTL
MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQV
NTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY
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| BDBM50124146 |
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| n/a |
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| Name | BDBM50124146 |
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| Synonyms: | CHEMBL3622801 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H66N8O8Si |
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| Mol. Mass. | 791.0649 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](C[Si](C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(O)=O |r| |
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| Structure | 
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