| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group I member 3 |
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| Ligand | BDBM50146172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1555044 (CHEMBL3767622) |
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| IC50 | 20±n/a nM |
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| Citation |  Lin, W; Yang, L; Chai, SC; Lu, Y; Chen, T Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor. Eur J Med Chem108:505-28 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 1 group I member 3 |
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| Name: | Nuclear receptor subfamily 1 group I member 3 |
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| Synonyms: | CAR | NR1I3 | NR1I3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39953.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1434936 |
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| Residue: | 352 |
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| Sequence: | MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
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| BDBM50146172 |
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| n/a |
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| Name | BDBM50146172 |
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| Synonyms: | CHEMBL3763664 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N3O3 |
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| Mol. Mass. | 415.4843 |
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| SMILES | O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CCC1 |
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| Structure | 
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