| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steryl-sulfatase |
|---|
| Ligand | BDBM50168245 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1577225 (CHEMBL3807716) |
|---|
| IC50 | 30±n/a nM |
|---|
| Citation |  Shah, R; Singh, J; Singh, D; Jaggi, AS; Singh, N Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review. Eur J Med Chem114:170-90 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steryl-sulfatase |
|---|
| Name: | Steryl-sulfatase |
|---|
| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 65503.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08842 |
|---|
| Residue: | 583 |
|---|
| Sequence: | MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLAS
GGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAK
LLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTT
GFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPL
NCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFA
GKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGS
NGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI
IDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNG
CFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQT
LPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
|
|
|
|---|
| BDBM50168245 |
|---|
| n/a |
|---|
| Name | BDBM50168245 |
|---|
| Synonyms: | CHEMBL3806272 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H33NO5S |
|---|
| Mol. Mass. | 471.609 |
|---|
| SMILES | [H][C@@]12CC[C@@](O)(Cc3ccc(OC)cc3)[C@@]1(C)CC[C@]1([H])c3ccc(OS(N)(=O)=O)cc3CC[C@@]21[H] |r| |
|---|
| Structure | 
|
|---|
Search and Browse
