Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bromodomain-containing protein 9 | ||
| Ligand | BDBM50172113 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1579124 (CHEMBL3811652) | ||
| Kd | >50000±n/a nM | ||
| Citation |  Unzue, A; Zhao, H; Lolli, G; Dong, J; Zhu, J; Zechner, M; Dolbois, A; Caflisch, A; Nevado, C The"Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains. J Med Chem59:3087-97 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bromodomain-containing protein 9 | |||
| Name: | Bromodomain-containing protein 9 | ||
| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 66994.30 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_108000 | ||
| Residue: | 597 | ||
| Sequence: |
| ||
| BDBM50172113 | |||
| n/a | |||
| Name | BDBM50172113 | ||
| Synonyms: | CHEMBL3809636 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H25N3O5 | ||
| Mol. Mass. | 447.4831 | ||
| SMILES | CCCOc1ccc2n(cc(-c3c(C)n([nH]c3=O)C(=O)c3ccc(OC)cc3)c2c1)C(C)=O |(-5.07,5.07,;-5.06,3.84,;-3.72,3.07,;-3.72,1.53,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;1.76,-1.24,;2.66,.02,;1.76,1.24,;2.23,2.7,;3.72,3.05,;4.66,2.25,;3.83,4.58,;2.4,5.16,;1.41,3.98,;.18,4.06,;5.13,5.4,;6.22,4.82,;5.08,6.94,;6.38,7.76,;6.33,9.3,;4.97,10.02,;4.9,11.56,;3.81,12.13,;3.66,9.2,;3.72,7.66,;.3,.77,;-1.03,1.55,;2.24,-2.7,;1.42,-3.62,;3.45,-2.94,)| | ||
| Structure | 
| ||