| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
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| Ligand | BDBM50174182 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1578757 |
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| IC50 | 160±n/a nM |
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| Citation |  Zhai, L; Zhang, YL; Kang, JS; Oelschlaeger, P; Xiao, L; Nie, SS; Yang, KW Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-ß-Lactmase-1 (NDM-1) Inhibitors. ACS Med Chem Lett7:413-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase type 2 |
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| Name: | Metallo-beta-lactamase type 2 |
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| Synonyms: | B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28498.15 |
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| Organism: | Klebsiella pneumoniae |
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| Description: | ChEMBL_103887 |
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| Residue: | 270 |
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| Sequence: | MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ
HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH
AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL
KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF
PKASMIVMSHSAPDSRAAITHTARMADKLR
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| BDBM50174182 |
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| n/a |
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| Name | BDBM50174182 |
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| Synonyms: | CHEMBL3809576 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13ClN4O2S |
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| Mol. Mass. | 360.818 |
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| SMILES | Oc1ccccc1-c1nnc(SCC(=O)Nc2cccc(Cl)c2)[nH]1 |
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| Structure | 
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