| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50252829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1661884 (CHEMBL4011496) |
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| Ki | 0.250000±n/a nM |
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| Citation |  Yu, J; Zhao, LX; Park, J; Lee, HW; Sahu, PK; Cui, M; Moss, SM; Hammes, E; Warnick, E; Gao, ZG; Noh, M; Choi, S; Ahn, HC; Choi, J; Jacobson, KA; Jeong, LS N J Med Chem60:3422-3437 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50252829 |
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| n/a |
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| Name | BDBM50252829 |
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| Synonyms: | (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrothiophene-2-carboxamide | CHEMBL522152 | N6-(3-Iodo-benzyl)-9-(5'-methylaminocarbonyl-4'-thiobeta-D-ribofuranosyl)adenine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19IN6O3S |
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| Mol. Mass. | 526.351 |
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| SMILES | CNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12 |r| |
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| Structure | 
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