Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Activated CDC42 kinase 1 | ||
| Ligand | BDBM98280 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | AlphaScreen Assay | ||
| IC50 | 114.6±n/a nM | ||
| Citation |  Crew, AP; Jin, M; Kadalbajoo, M; Kleinberg, A; Mulvihill, MJ; Wang, J Substituted imidazopyr- and imidazotri-azines US Patent US8481733 Publication Date 7/9/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Activated CDC42 kinase 1 | |||
| Name: | Activated CDC42 kinase 1 | ||
| Synonyms: | ACK1 | ACK1_HUMAN | Activated CDC42 kinase 1 (ACK-1) | TNK2 | Tyrosine kinase non-receptor protein 2 | ||
| Type: | Protein | ||
| Mol. Mass.: | 114577.86 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07912 | ||
| Residue: | 1038 | ||
| Sequence: |
| ||
| BDBM98280 | |||
| n/a | |||
| Name | BDBM98280 | ||
| Synonyms: | US8481733, 92 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H21FN4O2 | ||
| Mol. Mass. | 404.4368 | ||
| SMILES | C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc(Oc3ccccc3)c(F)c2)c2c(N)nccn12 |r,wU:4.6,1.1,wD:1.0,(1.33,-7.26,;-0,-6.49,;-.77,-7.83,;.77,-5.16,;-.56,-4.39,;-1.33,-5.72,;-.96,-2.9,;-.06,-1.65,;-.96,-.41,;-.56,1.08,;-1.65,2.17,;-1.25,3.65,;.23,4.05,;.63,5.54,;2.12,5.94,;3.21,4.85,;4.7,5.25,;5.09,6.74,;4.01,7.83,;2.52,7.43,;1.32,2.96,;2.81,3.36,;.92,1.48,;-2.43,-.88,;-3.76,-.11,;-3.76,1.43,;-5.09,-.88,;-5.09,-2.42,;-3.76,-3.19,;-2.43,-2.42,)| | ||
| Structure | 
| ||