| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium- and chloride-dependent glycine transporter 1 |
|---|
| Ligand | BDBM100936 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Uptake Inhibition Assay |
|---|
| Temperature | 273.15±n/a K |
|---|
| IC50 | 45.2±n/a nM |
|---|
| Citation |  Kolczewski, S; Pinard, E Tetrahydro-pyran derivatives US Patent US8524909 Publication Date 9/3/2013 |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Sodium- and chloride-dependent glycine transporter 1 |
|---|
| Name: | Sodium- and chloride-dependent glycine transporter 1 |
|---|
| Synonyms: | Glycine transporter 1b | SC6A9_BOVIN | SLC6A9 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 71324.09 |
|---|
| Organism: | Bos taurus (Bovine) |
|---|
| Description: | Q28039 |
|---|
| Residue: | 638 |
|---|
| Sequence: | MAAAQGPVAPSSLEQNGAVPSEATKKDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPY
LCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVV
STYIGIYYNVVICIAFYYFFSSMTPVLPWTYCNNPWNTPDCMSVLDNPNITNGSQPPALP
GNVSQALNQTLKRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRG
VKSSGKVVYFTATFPYVVLTILFIRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQI
FYSLGCAWGGLVTMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVD
VSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEV
GNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVIISCIMCVSIM
YIYGHQNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFSVIQYQPITYNQYQYPSW
RVRIGFLMALSSVICIPLYALFQFCRTDGDTLLHRLKNATKPSRDWGPALLEHRTRRYAP
TTTPSPEDGLEVQPLHPDKAQIPMVGSNGSSRFQDSRI
|
|
|
|---|
| BDBM100936 |
|---|
| n/a |
|---|
| Name | BDBM100936 |
|---|
| Synonyms: | US8524909, 123 | US8524909, 21 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H25F3N2O2 |
|---|
| Mol. Mass. | 370.4092 |
|---|
| SMILES | Cc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
