| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [33-574] |
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| Ligand | BDBM108251 |
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| Substrate/Competitor | n/a |
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| IC50 | 95±14 nM |
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| Citation |  Lambruschini, C; Veronesi, M; Romeo, E; Garau, G; Bandiera, T; Piomelli, D; Scarpelli, R; Dalvit, C Development of fragment-based n-FABS NMR screening applied to the membrane enzyme FAAH. Chembiochem14:1611-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Fatty-acid amide hydrolase 1 [33-574] |
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| Name: | Fatty-acid amide hydrolase 1 [33-574] |
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| Synonyms: | FAAH1_RAT | Faah | Faah1 | Fatty-acid amide hydrolase (rFAAH∆TM) |
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| Type: | Protein |
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| Mol. Mass.: | 59459.86 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | 97-1722bp |
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| Residue: | 542 |
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| Sequence: | GRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELS
PEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDS
TLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSK
SPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYG
QTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYET
DNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNF
KGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIE
MYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTV
TAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLM
TP
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| BDBM108251 |
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| n/a |
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| Name | BDBM108251 |
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| Synonyms: | 2,3‐dichloro‐N‐{1H‐pyrrolo[2,3‐b]pyridin‐5‐ yl}benzamide (Compound 2) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9Cl2N3O |
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| Mol. Mass. | 306.147 |
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| SMILES | Clc1cccc(C(=O)Nc2cnc3[nH]ccc3c2)c1Cl |
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| Structure | 
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