| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T] |
|---|
| Ligand | BDBM114221 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of phospholipase C isozymes (PLC-B3): Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1) |
|---|
| IC50 | 107767±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of phospholipase C isozymes (PLC-B3): Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1) PubChem Bioassay(2014)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T] |
|---|
| Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T] |
|---|
| Synonyms: | PLC1 | PLCG1 | PLCG1_HUMAN | Phospholipase C, gamma 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 115282.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_223459640 |
|---|
| Residue: | 999 |
|---|
| Sequence: | MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKK
|
|
|
|---|
| BDBM114221 |
|---|
| n/a |
|---|
| Name | BDBM114221 |
|---|
| Synonyms: | (5Z)-5-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)-N-(phenylmethyl)-1,2-dihydro-1,2,3-triazole-4-carboxamide | (5Z)-5-(6-oxo-1-cyclohexa-2,4-dienylidene)-N-(phenylmethyl)-1,2-dihydrotriazole-4-carboxamide | (5Z)-N-benzyl-5-(6-ketocyclohexa-2,4-dien-1-ylidene)-1,2-dihydrotriazole-4-carboxamide | (5Z)-N-benzyl-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2-dihydrotriazole-4-carboxamide | MLS000053062 | N-benzyl-5-(2-hydroxyphenyl)-1H-1,2,3-triazole-4-carboxamide | SMR000069330 | cid_5368408 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N4O2 |
|---|
| Mol. Mass. | 294.308 |
|---|
| SMILES | Oc1ccccc1-c1nn[nH]c1C(=O)NCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
