| Reaction Details |
|---|
 | Report a problem with these data |
| Target | PC4 and SFRS1-interacting protein |
|---|
| Ligand | BDBM50027326 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration |
|---|
| IC50 | 3226±n/a nM |
|---|
| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration PubChem Bioassay(2014)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| PC4 and SFRS1-interacting protein |
|---|
| Name: | PC4 and SFRS1-interacting protein |
|---|
| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 60120.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_6708281 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
|
|
|
|---|
| BDBM50027326 |
|---|
| n/a |
|---|
| Name | BDBM50027326 |
|---|
| Synonyms: | (1R)-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol | (R)-norlaudanosoline | CHEMBL156383 | cid_440990 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H17NO4 |
|---|
| Mol. Mass. | 287.3105 |
|---|
| SMILES | Oc1ccc(C[C@H]2NCCc3cc(O)c(O)cc23)cc1O |
|---|
| Structure | 
|
|---|
Search and Browse
