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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120366 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 68.1±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120366 | |||
| n/a | |||
| Name | BDBM120366 | ||
| Synonyms: | US8703807, 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H27F3N2O3 | ||
| Mol. Mass. | 424.4566 | ||
| SMILES | O[C@@]1(CN2CCCCC2=O)CC[C@]2(CCN(C2=O)c2ccc(cc2)C(F)(F)F)CC1 |r,wU:12.17,1.0,wD:1.1,(-4.96,.59,;-3.88,-.5,;-5.36,-.9,;-6.45,.19,;-6.05,1.68,;-7.14,2.76,;-8.63,2.37,;-9.03,.88,;-7.94,-.21,;-8.34,-1.7,;-2.79,.59,;-1.3,.19,;-.9,-1.3,;-.42,-2.76,;1.12,-2.76,;1.59,-1.3,;.35,-.39,;.35,1.15,;3.08,-.9,;4.17,-1.99,;5.66,-1.59,;6.05,-.1,;4.96,.99,;3.48,.59,;7.54,.29,;8.63,-.79,;7.94,1.78,;9.03,.69,;-1.99,-2.39,;-3.48,-1.99,)| | ||
| Structure | 
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