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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120367 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 50.9±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120367 | |||
| n/a | |||
| Name | BDBM120367 | ||
| Synonyms: | US8703807, 3 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H32N2O4 | ||
| Mol. Mass. | 400.5112 | ||
| SMILES | CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(CN3CCCC3=O)CC2)C1=O |r,wU:13.29,16.17,wD:16.18,(9.44,-.29,;7.95,-.69,;7.55,-2.18,;6.86,.4,;5.38,-0,;4.98,-1.49,;3.49,-1.89,;2.4,-.8,;2.8,.69,;4.29,1.09,;.91,-1.2,;.44,-2.66,;-1.1,-2.66,;-1.58,-1.2,;-1.98,.29,;-3.46,.69,;-4.55,-.4,;-5.64,.69,;-6.04,-.8,;-7.13,.29,;-6.65,1.76,;-7.9,2.66,;-9.15,1.76,;-8.67,.29,;-9.44,-1.04,;-4.15,-1.89,;-2.67,-2.29,;-.33,-.29,;-.33,1.25,)| | ||
| Structure | 
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