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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120368 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 27.4±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120368 | |||
| n/a | |||
| Name | BDBM120368 | ||
| Synonyms: | US8703807, 4 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H34N2O4 | ||
| Mol. Mass. | 414.5378 | ||
| SMILES | CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(CN3CCCCC3=O)CC2)C1=O |r,wU:13.30,16.17,wD:16.18,(9.57,-.4,;8.09,-.79,;7.69,-2.28,;7,.29,;5.51,-.1,;5.11,-1.59,;3.62,-1.99,;2.53,-.9,;2.93,.59,;4.42,.99,;1.05,-1.3,;.57,-2.76,;-.97,-2.76,;-1.45,-1.3,;-1.84,.19,;-3.33,.59,;-4.42,-.5,;-5.51,.59,;-5.91,-.9,;-7,.19,;-6.6,1.68,;-7.69,2.76,;-9.17,2.37,;-9.57,.88,;-8.48,-.21,;-8.88,-1.7,;-4.02,-1.99,;-2.53,-2.39,;-.2,-.39,;-.2,1.15,)| | ||
| Structure | 
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