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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120370 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 264±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120370 | |||
| n/a | |||
| Name | BDBM120370 | ||
| Synonyms: | US8703807, 6 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31N3O4 | ||
| Mol. Mass. | 401.4992 | ||
| SMILES | CC(C)Oc1ccc(cn1)N1CC[C@]2(CC[C@@](O)(CN3CCCC3=O)CC2)C1=O |r,wU:13.29,16.17,wD:16.18,(9.36,-.14,;7.87,-.54,;7.48,-2.03,;6.78,.55,;5.3,.15,;4.9,-1.34,;3.41,-1.74,;2.32,-.65,;2.72,.84,;4.21,1.24,;.83,-1.05,;.36,-2.51,;-1.18,-2.51,;-1.66,-1.05,;-1.66,.49,;-2.99,1.26,;-4.32,.49,;-5.09,1.83,;-5.66,-.28,;-6.99,.49,;-6.99,2.03,;-8.46,2.51,;-9.36,1.26,;-8.46,.02,;-9.23,-1.32,;-4.32,-1.05,;-2.99,-1.82,;-.41,-.14,;-.41,1.4,)| | ||
| Structure | 
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