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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120371 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 13.7±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120371 | |||
| n/a | |||
| Name | BDBM120371 | ||
| Synonyms: | US8703807, 7 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H27F3N2O4 | ||
| Mol. Mass. | 416.4346 | ||
| SMILES | CC(C)Oc1ccc(cn1)N1CC[C@]2(CC[C@@](O)(COCC(F)(F)F)CC2)C1=O |r,wU:13.28,16.17,wD:16.18,(9.92,.7,;8.44,.3,;8.04,-1.19,;7.35,1.39,;5.86,.99,;5.46,-.5,;3.97,-.9,;2.88,.19,;3.28,1.68,;4.77,2.08,;1.4,-.21,;.92,-1.67,;-.62,-1.67,;-1.1,-.21,;-1.1,1.33,;-2.43,2.1,;-3.76,1.33,;-4.53,2.67,;-5.3,1.33,;-6.07,,;-7.61,,;-8.38,-1.33,;-9.92,-1.33,;-7.61,-2.67,;-9.15,-2.67,;-3.76,-.21,;-2.43,-.98,;.15,.7,;.15,2.24,)| | ||
| Structure | 
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