Reaction Details | |||
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Report a problem with these data | |||
Target | Hormone-sensitive lipase | ||
Ligand | BDBM120373 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzyme Inhibition Assay | ||
pH | 7.2±n/a | ||
Temperature | 277.15±n/a K | ||
IC50 | 30.6±n/a nM | ||
Comments | extracted | ||
Citation | Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Hormone-sensitive lipase | |||
Name: | Hormone-sensitive lipase | ||
Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
Type: | Protein | ||
Mol. Mass.: | 116599.07 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q05469 | ||
Residue: | 1076 | ||
Sequence: |
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BDBM120373 | |||
n/a | |||
Name | BDBM120373 | ||
Synonyms: | US8703807, 9 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H29F3N2O4 | ||
Mol. Mass. | 454.4826 | ||
SMILES | C[C@@H](Oc1ccc(cc1)N1CCC2(CC[C@@](O)(CN3CCCC3=O)CC2)C1=O)C(F)(F)F |r,wU:15.17,wD:1.0,15.16,(5.24,1.95,;6.33,.86,;5.93,-.63,;4.45,-1.02,;4.05,-2.51,;2.56,-2.91,;1.47,-1.82,;1.87,-.33,;3.36,.06,;-.02,-2.22,;-.49,-3.68,;-2.03,-3.68,;-2.51,-2.22,;-3.6,-3.31,;-5.08,-2.91,;-5.48,-1.42,;-6.57,-2.51,;-5.48,.12,;-6.82,.89,;-8.06,-.02,;-9.31,.89,;-8.83,2.35,;-7.29,2.35,;-6.52,3.68,;-4.39,-.33,;-2.91,-.73,;-1.26,-1.32,;-1.26,.22,;7.82,1.26,;8.91,.17,;9.31,1.66,;8.22,2.75,)| | ||
Structure |