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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120375 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120375 | |||
| n/a | |||
| Name | BDBM120375 | ||
| Synonyms: | US8703807, 11 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H26F4N2O4 | ||
| Mol. Mass. | 434.4251 | ||
| SMILES | C[C@H](Oc1ccc(cn1)N1CC[C@]2(CC[C@@](O)(COCCF)CC2)C1=O)C(F)(F)F |r,wU:15.16,wD:12.12,1.0,15.17,(7.55,-1.47,;7.95,.02,;6.86,1.1,;5.38,.71,;4.98,-.78,;3.49,-1.18,;2.4,-.09,;2.8,1.4,;4.29,1.79,;.91,-.49,;.44,-1.95,;-1.1,-1.95,;-1.58,-.49,;-1.98,1,;-3.46,1.4,;-4.55,.31,;-5.32,1.64,;-6.09,.31,;-6.86,-1.03,;-8.35,-.63,;-9.44,-1.72,;-10.93,-1.32,;-4.15,-1.18,;-2.67,-1.58,;-.33,.41,;-.33,1.95,;9.44,.41,;9.84,1.9,;10.53,-.68,;10.93,.81,)| | ||
| Structure | 
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