Reaction Details |
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Target | Orexin receptor type 2 |
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Ligand | BDBM123328 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Radioligand Binding Assay I |
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pH | 7.5±n/a |
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Temperature | 277.15±n/a K |
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Kd | 143±n/a nM |
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Comments | extracted |
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Citation | Badiger, S; Behnke, D; Betschart, C; Chaudhari, V; Chebrolu, M; Cotesta, S; Hintermann, S; Meyer, A; Pandit, C Disubstituted heteroaryl-fused pyridines US Patent US8742106 Publication Date 6/3/2014 |
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More Info.: | Get all data from this article, Assay Method |
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Orexin receptor type 2 |
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Name: | Orexin receptor type 2 |
Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R |
Type: | Protein |
Mol. Mass.: | 50710.53 |
Organism: | Homo sapiens (Human) |
Description: | O43614 |
Residue: | 444 |
Sequence: | MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
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BDBM123328 |
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n/a |
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Name | BDBM123328 |
Synonyms: | US8742106, 1.13 |
Type | Small organic molecule |
Emp. Form. | C24H24N4O2 |
Mol. Mass. | 400.473 |
SMILES | C[C@H](NC(=O)COc1cc(C)c2c(nn(C)c2n1)-c1ccccc1)c1ccccc1 |r| |
Structure |
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