Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Serine/threonine-protein kinase mTOR | ||
Ligand | BDBM127455 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay | ||
pH | 7.5±n/a | ||
Temperature | 298.15±n/a K | ||
Ki | 0.33±n/a nM | ||
Comments | extracted | ||
Citation | Cheng, H; Johnson, TW; Hoffman, JE; Guo, LC; Liu, Z Imidazo[1,5]naphthyridine compounds, their pharmaceutical use and compositions US Patent US8791131 Publication Date 7/29/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Serine/threonine-protein kinase mTOR | |||
Name: | Serine/threonine-protein kinase mTOR | ||
Synonyms: | FK506-binding protein 12-rapamycin complex-associated protein 1 | FKBP12-rapamycin complex-associated protein | FRAP | FRAP 1 (mTOR) | FRAP1 | FRAP2 | MTOR | MTOR_HUMAN | Mammalian Target of Rapamycin (mTOR) | P42345 | RAFT1 | RAPT1 | Rapamycin and FKBP12 target 1 | Rapamycin target protein | Serine/threonine-protein kinase (mTOR) | mTORC2 | ||
Type: | Rapamycin target protein | ||
Mol. Mass.: | 288917.12 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P42345 | ||
Residue: | 2549 | ||
Sequence: |
| ||
BDBM127455 | |||
n/a | |||
Name | BDBM127455 | ||
Synonyms: | US8791131, 229 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H21N7O2 | ||
Mol. Mass. | 391.4264 | ||
SMILES | Cn1c2cnc3ccc(nc3c2n([C@H]2CC[C@H](O)CC2)c1=O)-c1cnc(N)nc1 |r,wU:13.14,wD:16.18,(6.65,-1.53,;5.16,-1.13,;4.02,-2.16,;4.02,-3.7,;2.69,-4.47,;1.35,-3.7,;.02,-4.47,;-1.32,-3.7,;-1.32,-2.16,;.02,-1.39,;1.35,-2.16,;2.69,-1.39,;3.01,.12,;1.92,1.2,;.43,.81,;-.66,1.89,;-.26,3.38,;-1.35,4.47,;1.23,3.78,;2.31,2.69,;4.54,.28,;5.31,1.61,;-2.65,-1.39,;-2.65,.15,;-3.98,.92,;-5.32,.15,;-6.65,.92,;-5.32,-1.39,;-3.98,-2.16,)| | ||
Structure |