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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102532 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 139±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
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| BDBM102532 | |||
| n/a | |||
| Name | BDBM102532 | ||
| Synonyms: | US8536175, 112 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H30Cl2N6O3 | ||
| Mol. Mass. | 581.493 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(CN3CCNC(C)(C)C3)nc2)c2nccnc12 |(8.7,-13.78,;7.36,-14.55,;7.36,-16.09,;8.7,-16.86,;8.7,-18.4,;10.03,-19.17,;11.36,-18.4,;7.36,-19.17,;7.36,-20.71,;6.03,-18.4,;6.03,-16.86,;4.69,-16.09,;4.69,-19.17,;3.36,-18.4,;2.03,-19.17,;2.03,-20.71,;.69,-21.48,;.69,-23.02,;-.64,-20.71,;-1.97,-21.48,;-3.31,-20.71,;-4.64,-21.48,;-4.64,-23.02,;-5.98,-23.79,;-7.31,-23.02,;-7.31,-21.48,;-8.64,-20.71,;-9.98,-21.48,;-9.98,-23.02,;-11.31,-23.79,;-10.38,-24.51,;-8.64,-23.79,;-3.31,-23.79,;-1.97,-23.02,;3.36,-21.48,;3.36,-23.02,;4.69,-23.79,;6.03,-23.02,;6.03,-21.48,;4.69,-20.71,)| | ||
| Structure | 
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