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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102533 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 14±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102533 | |||
| n/a | |||
| Name | BDBM102533 | ||
| Synonyms: | US8536175, 122 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H32Cl2N6O3 | ||
| Mol. Mass. | 595.519 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cn2)c2nc(C)c(C)nc12 |(10.39,-2,;8.85,-2,;8.08,-.67,;8.85,.67,;8.08,2,;8.85,3.33,;8.08,4.67,;6.54,2,;5.78,3.33,;5.78,.67,;6.54,-.67,;5.78,-2,;4.23,.67,;3.47,2,;1.93,2,;1.15,.67,;-.38,.67,;-1.15,2,;-1.15,-.67,;-2.69,-.67,;-3.47,.67,;-5,.67,;-5.78,-.67,;-7.31,-.67,;-8.08,.67,;-7.31,2,;-8.08,3.33,;-9.63,3.33,;-10.39,4.67,;-10.39,2,;-9.63,.67,;-5,-2,;-3.47,-2,;1.93,-.67,;1.15,-2,;1.93,-3.33,;1.15,-4.67,;3.47,-3.33,;4.23,-4.67,;4.23,-2,;3.47,-.67,)| | ||
| Structure | 
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