Reaction Details | |||
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Target | C-C chemokine receptor type 2 | ||
Ligand | BDBM141953 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Binding Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 590±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
C-C chemokine receptor type 2 | |||
Name: | C-C chemokine receptor type 2 | ||
Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
Type: | Enzyme | ||
Mol. Mass.: | 41932.32 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41597 | ||
Residue: | 374 | ||
Sequence: |
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BDBM141953 | |||
n/a | |||
Name | BDBM141953 | ||
Synonyms: | US8921559, 48 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H36N6O2 | ||
Mol. Mass. | 488.6244 | ||
SMILES | Cc1cccc(NC(=O)N2CCC(CC2)C(NC2CCC(CC2)c2c[nH]c3cccnc23)C(N)=O)c1 |(10.52,-3.05,;9.19,-3.82,;9.19,-5.36,;7.85,-6.13,;6.52,-5.36,;6.52,-3.82,;5.19,-3.05,;3.85,-3.82,;3.85,-5.36,;2.52,-3.05,;2.52,-1.51,;1.18,-.74,;-.15,-1.51,;-.15,-3.05,;1.18,-3.82,;-1.48,-.74,;-2.82,-1.51,;-4.15,-.74,;-5.48,-1.51,;-6.82,-.74,;-6.82,.8,;-5.48,1.57,;-4.15,.8,;-8.15,1.57,;-9.62,1.1,;-10.52,2.34,;-9.62,3.59,;-9.94,5.1,;-8.79,6.13,;-7.33,5.65,;-7.01,4.14,;-8.15,3.11,;-1.48,.8,;-.15,1.57,;-2.82,1.57,;7.85,-3.05,)| | ||
Structure | ![]() |