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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium channel protein type 9 subunit alpha | ||
| Ligand | BDBM145632 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 3±n/a nM | ||
| Comments | extracted | ||
| Citation |  Andrez, J; Chowdhury, S; Decker, SM; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Li, J; Ortwine, DF; Safina, B; Sheng, T; Sun, S; Sutherlin, DP; Wilson, MS; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US8952169 Publication Date 2/10/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium channel protein type 9 subunit alpha | |||
| Name: | Sodium channel protein type 9 subunit alpha | ||
| Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
| Type: | Protein | ||
| Mol. Mass.: | 226375.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15858 | ||
| Residue: | 1988 | ||
| Sequence: |
| ||
| BDBM145632 | |||
| n/a | |||
| Name | BDBM145632 | ||
| Synonyms: | US8952169, 435 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H25F4NO4S | ||
| Mol. Mass. | 463.486 | ||
| SMILES | Fc1cc(OCC2CC[C@@H](CC2)C(F)(F)F)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1 |r,wU:9.12,(3.9,.77,;2.56,,;1.23,.77,;-.1,,;-1.44,.77,;-2.77,,;-4.1,.77,;-4.1,2.31,;-5.44,3.08,;-6.77,2.31,;-6.77,.77,;-5.44,,;-8.11,3.08,;-9.44,3.85,;-7.34,4.41,;-8.88,1.75,;-.1,-1.54,;1.23,-2.31,;2.56,-1.54,;3.9,-2.31,;3.9,-3.85,;5.23,-1.54,;6.57,-2.31,;5.8,-3.64,;7.34,-.98,;7.9,-3.08,;8.67,-4.41,;9.44,-3.08,;-1.44,-2.31,;-2.98,-2.31,;-2.21,-3.64,)| | ||
| Structure | 
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