Reaction Details | |||
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Target | Sodium channel protein type 9 subunit alpha | ||
Ligand | BDBM145610 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Electrophysiological Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 3±n/a nM | ||
Comments | extracted | ||
Citation | Andrez, J; Chowdhury, S; Decker, SM; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Li, J; Ortwine, DF; Safina, B; Sheng, T; Sun, S; Sutherlin, DP; Wilson, MS; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US8952169 Publication Date 2/10/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Sodium channel protein type 9 subunit alpha | |||
Name: | Sodium channel protein type 9 subunit alpha | ||
Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
Type: | Protein | ||
Mol. Mass.: | 226375.97 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15858 | ||
Residue: | 1988 | ||
Sequence: |
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BDBM145610 | |||
n/a | |||
Name | BDBM145610 | ||
Synonyms: | US8952169, 413 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H28FNO4S | ||
Mol. Mass. | 409.515 | ||
SMILES | CC1CCC(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)C2CC2)CC1 |w:5.4,1.0,(-8.77,-3.18,;-7.44,-2.41,;-7.44,-.87,;-6.1,-.1,;-4.77,-.87,;-3.44,-.1,;-2.1,-.87,;-.77,-.1,;-.77,1.44,;.56,2.21,;.56,3.75,;1.9,1.44,;1.9,-.1,;.56,-.87,;.56,-2.41,;-.21,-3.75,;1.33,-3.75,;3.23,2.21,;3.23,3.75,;4.56,1.44,;5.9,2.21,;5.13,3.54,;6.67,3.54,;7.23,1.44,;8,.1,;8.77,1.44,;-4.77,-2.41,;-6.1,-3.18,)| | ||
Structure |