Reaction Details |
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Target | Vasopressin V2 receptor |
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Ligand | BDBM192471 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Cellular In Vitro Assay |
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Temperature | 310.15±n/a K |
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IC50 | 45±n/a nM |
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Comments | extracted |
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Citation | Fürstner, C; Keldenich, J; Delbeck, M; Kolkhof, P; Kretschmer, A; Pluschkell, I; Pook, E; Schmeck, C; Trübel, H Bisaryl-bonded aryltriazolones and use thereof US Patent US9687476 Publication Date 6/27/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Vasopressin V2 receptor |
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Name: | Vasopressin V2 receptor |
Synonyms: | ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor |
Type: | Receptor |
Mol. Mass.: | 40295.28 |
Organism: | Homo sapiens (Human) |
Description: | P30518 |
Residue: | 371 |
Sequence: | MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
ASSSLAKDTSS
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BDBM192471 |
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n/a |
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Name | BDBM192471 |
Synonyms: | US9187466, 117 | US9687476, 117 |
Type | Small organic molecule |
Emp. Form. | C21H15ClF6N6O4S |
Mol. Mass. | 596.89 |
SMILES | OC(Cn1c(nn(c1=O)S(=O)(=O)c1ncnn1Cc1ccccc1C(F)(F)F)-c1ccc(Cl)cc1)C(F)(F)F |
Structure |
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