Compile Data Set for Download or QSAR

Found 555 hits with Last Name = 'fürstner' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM190298 (US9180120, 2) Show SMILES NC(=O)OCC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C24H22ClF6N5O5/c25-15-7-5-13(6-8-15)20-34-36(22(40)35(20)10-18(37)24(29,30)31)11-19(38)33-9-14(12-41-21(32)39)16-3-1-2-4-17(16)23(26,27)28/h1-8,14,18,37H,9-12H2,(H2,32,39)(H,33,38)/t14?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtitre plates an...				US Patent US9180120 (2015) BindingDB Entry DOI: 10.7270/Q2KK99KH
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM190302 (US9180120, 6) Show SMILES NC(=O)OCC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1ccccc1Cl |r| Show InChI InChI=1S/C23H22Cl2F3N5O5/c24-15-7-5-13(6-8-15)20-31-33(22(37)32(20)10-18(34)23(26,27)28)11-19(35)30-9-14(12-38-21(29)36)16-3-1-2-4-17(16)25/h1-8,14,18,34H,9-12H2,(H2,29,36)(H,30,35)/t14?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtitre plates an...				US Patent US9180120 (2015) BindingDB Entry DOI: 10.7270/Q2KK99KH
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255962 (US9481672, 140) Show SMILES CCn1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C23H18ClF3N4O5/c1-3-29-17-9-13(7-8-16(17)28(2)21(29)35)30-11-14(20(33)34)19(32)31(22(30)36)10-12-5-4-6-15(18(12)24)23(25,26)27/h4-9,11H,3,10H2,1-2H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255964 (US9481672, 142) Show SMILES Cn1c2ccc(cc2n(CC(F)(F)F)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O Show InChI InChI=1S/C23H15ClF6N4O5/c1-31-15-6-5-12(7-16(15)34(20(31)38)10-22(25,26)27)32-9-13(19(36)37)18(35)33(21(32)39)8-11-3-2-4-14(24)17(11)23(28,29)30/h2-7,9H,8,10H2,1H3,(H,36,37)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255968 (US9481672, 146) Show SMILES Cc1c(Cn2c(=O)c(cn(-c3ccc4n(C)c(=O)n(CC5CC5)c4c3)c2=O)C(O)=O)cccc1C(F)(F)F Show InChI InChI=1S/C26H23F3N4O5/c1-14-16(4-3-5-19(14)26(27,28)29)12-33-22(34)18(23(35)36)13-31(25(33)38)17-8-9-20-21(10-17)32(11-15-6-7-15)24(37)30(20)2/h3-5,8-10,13,15H,6-7,11-12H2,1-2H3,(H,35,36)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256036 (US9481672, 217) Show SMILES CC(C)n1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H23F3N4O5/c1-13(2)32-21-11-14(7-9-20(21)30(3)24(32)37)31-12-17(23(35)36)22(34)33(25(31)38)19-10-8-15-16(19)5-4-6-18(15)26(27,28)29/h4-7,9,11-13,19H,8,10H2,1-3H3,(H,35,36)/t19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256064 (US9481672, 246) Show SMILES Cn1c2ccc(cc2n(CC(O)C(F)(F)F)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H20F6N4O6/c1-33-18-7-5-12(9-19(18)35(23(33)41)11-20(37)26(30,31)32)34-10-15(22(39)40)21(38)36(24(34)42)17-8-6-13-14(17)3-2-4-16(13)25(27,28)29/h2-5,7,9-10,17,20,37H,6,8,11H2,1H3,(H,39,40)/t17-,20?/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256065 (US9481672, 247) Show SMILES Cn1c2ccc(cc2n(CCC(F)(F)F)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H20F6N4O5/c1-33-19-7-5-13(11-20(19)34(23(33)40)10-9-25(27,28)29)35-12-16(22(38)39)21(37)36(24(35)41)18-8-6-14-15(18)3-2-4-17(14)26(30,31)32/h2-5,7,11-12,18H,6,8-10H2,1H3,(H,38,39)/t18-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256099 (US9481672, 281) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C25H21F3N4O5/c1-29-19-10-9-13(11-20(19)30(2)23(29)36)31-12-16(22(34)35)21(33)32(24(31)37)18-8-4-5-14-15(18)6-3-7-17(14)25(26,27)28/h3,6-7,9-12,18H,4-5,8H2,1-2H3,(H,34,35)/t18-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM192452 (US9187466, 50 | US9687476, 50) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(Cc3ccccc3F)[nH]2)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	37
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9687476 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6QDG
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM192451 (US9187466, 49 | US9687476, 49) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(Cc3ccccc3Cl)[nH]2)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	37
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9687476 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6QDG
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM88376 (US9695131, 13) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(-c2nnn[nH]2)c(=O)n(C2CCc3c2cccc3C(F)(F)F)c1=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9695131 (2017) BindingDB Entry DOI: 10.7270/Q2ZP448Z
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM190343 (US9180120, 47) Show SMILES NC(=O)OC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1ccccc1Cl |r| Show InChI InChI=1S/C22H20Cl2F3N5O5/c23-13-7-5-12(6-8-13)19-30-32(21(36)31(19)10-17(33)22(25,26)27)11-18(34)29-9-16(37-20(28)35)14-3-1-2-4-15(14)24/h1-8,16-17,33H,9-11H2,(H2,28,35)(H,29,34)/t16?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtitre plates an...				US Patent US9180120 (2015) BindingDB Entry DOI: 10.7270/Q2KK99KH
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM190348 (US9180120, 52) Show SMILES NC(=O)OC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C22H19Cl3F3N5O5/c23-12-6-4-11(5-7-12)19-31-33(21(37)32(19)9-16(34)22(26,27)28)10-17(35)30-8-15(38-20(29)36)13-2-1-3-14(24)18(13)25/h1-7,15-16,34H,8-10H2,(H2,29,36)(H,30,35)/t15?,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtitre plates an...				US Patent US9180120 (2015) BindingDB Entry DOI: 10.7270/Q2KK99KH
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255927 (US9481672, 104) Show SMILES CCOC(=O)c1cn(-c2cc3n(C)c(=O)n(C)c3cc2F)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H22F4N4O5/c1-4-39-23(36)15-12-33(19-11-21-20(10-17(19)27)31(2)24(37)32(21)3)25(38)34(22(15)35)18-9-8-13-14(18)6-5-7-16(13)26(28,29)30/h5-7,10-12,18H,4,8-9H2,1-3H3/t18-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255944 (US9481672, 122) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C(F)(F)F)C(F)(F)F)c1=O Show InChI InChI=1S/C23H16F6N4O5/c1-30-15-7-6-12(8-16(15)31(2)20(30)37)32-10-13(19(35)36)18(34)33(21(32)38)9-11-4-3-5-14(22(24,25)26)17(11)23(27,28)29/h3-8,10H,9H2,1-2H3,(H,35,36)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255954 (US9481672, 132) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C24H19F3N4O5/c1-28-18-8-6-12(10-19(18)29(2)22(28)35)30-11-15(21(33)34)20(32)31(23(30)36)17-9-7-13-14(17)4-3-5-16(13)24(25,26)27/h3-6,8,10-11,17H,7,9H2,1-2H3,(H,33,34)/t17-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255956 (US9481672, 134) Show SMILES Cn1c2cc(F)c(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C24H18F4N4O5/c1-29-18-8-15(25)17(9-19(18)30(2)22(29)36)31-10-13(21(34)35)20(33)32(23(31)37)16-7-6-11-12(16)4-3-5-14(11)24(26,27)28/h3-5,8-10,16H,6-7H2,1-2H3,(H,34,35)/t16-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255958 (US9481672, 136) Show SMILES CCn1c2ccc(cc2n(CC)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O Show InChI InChI=1S/C25H23F3N4O5/c1-4-29-19-10-9-16(11-20(19)30(5-2)23(29)36)31-13-17(22(34)35)21(33)32(24(31)37)12-15-7-6-8-18(14(15)3)25(26,27)28/h6-11,13H,4-5,12H2,1-3H3,(H,34,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255961 (US9481672, 139) Show SMILES CCn1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O Show InChI InChI=1S/C23H18ClF3N4O5/c1-3-29-17-9-13(7-8-16(17)28(2)21(29)35)30-11-14(20(33)34)19(32)31(22(30)36)10-12-5-4-6-15(24)18(12)23(25,26)27/h4-9,11H,3,10H2,1-2H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255963 (US9481672, 141) Show SMILES CCn1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O Show InChI InChI=1S/C24H21F3N4O5/c1-4-29-19-10-15(8-9-18(19)28(3)22(29)35)30-12-16(21(33)34)20(32)31(23(30)36)11-14-6-5-7-17(13(14)2)24(25,26)27/h5-10,12H,4,11H2,1-3H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255965 (US9481672, 143) Show SMILES Cn1c2ccc(cc2n(CC(F)(F)F)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C23H15ClF6N4O5/c1-31-15-6-5-12(7-16(15)34(20(31)38)10-22(25,26)27)32-9-13(19(36)37)18(35)33(21(32)39)8-11-3-2-4-14(17(11)24)23(28,29)30/h2-7,9H,8,10H2,1H3,(H,36,37)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255966 (US9481672, 144) Show SMILES Cc1c(Cn2c(=O)c(cn(-c3ccc4n(C)c(=O)n(CC(F)(F)F)c4c3)c2=O)C(O)=O)cccc1C(F)(F)F Show InChI InChI=1S/C24H18F6N4O5/c1-12-13(4-3-5-16(12)24(28,29)30)9-33-19(35)15(20(36)37)10-32(22(33)39)14-6-7-17-18(8-14)34(11-23(25,26)27)21(38)31(17)2/h3-8,10H,9,11H2,1-2H3,(H,36,37)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255967 (US9481672, 145) Show SMILES Cn1c2ccc(cc2n(CC2CC2)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C25H20ClF3N4O5/c1-30-18-8-7-15(9-19(18)32(23(30)37)10-13-5-6-13)31-12-16(22(35)36)21(34)33(24(31)38)11-14-3-2-4-17(20(14)26)25(27,28)29/h2-4,7-9,12-13H,5-6,10-11H2,1H3,(H,35,36)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255969 (US9481672, 147) Show SMILES Cn1c2ccc(cc2n(CC2CC2)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O Show InChI InChI=1S/C25H20ClF3N4O5/c1-30-18-8-7-15(9-19(18)32(23(30)37)10-13-5-6-13)31-12-16(22(35)36)21(34)33(24(31)38)11-14-3-2-4-17(26)20(14)25(27,28)29/h2-4,7-9,12-13H,5-6,10-11H2,1H3,(H,35,36)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255971 (US9481672, 149) Show SMILES Cc1c(Cn2c(=O)c(cn(-c3ccc4n(C)c(=O)n(C5CCC5)c4c3)c2=O)C(O)=O)cccc1C(F)(F)F Show InChI InChI=1S/C26H23F3N4O5/c1-14-15(5-3-8-19(14)26(27,28)29)12-32-22(34)18(23(35)36)13-31(25(32)38)17-9-10-20-21(11-17)33(16-6-4-7-16)24(37)30(20)2/h3,5,8-11,13,16H,4,6-7,12H2,1-2H3,(H,35,36)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255973 (US9481672, 151) Show SMILES CC(C)n1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O Show InChI InChI=1S/C25H23F3N4O5/c1-13(2)32-20-10-16(8-9-19(20)29(4)23(32)36)30-12-17(22(34)35)21(33)31(24(30)37)11-15-6-5-7-18(14(15)3)25(26,27)28/h5-10,12-13H,11H2,1-4H3,(H,34,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256043 (US9481672, 224) Show SMILES CN1C(=O)C(C)(C)c2cc(ccc12)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H22F3N3O5/c1-25(2)18-11-13(7-9-20(18)30(3)23(25)36)31-12-16(22(34)35)21(33)32(24(31)37)19-10-8-14-15(19)5-4-6-17(14)26(27,28)29/h4-7,9,11-12,19H,8,10H2,1-3H3,(H,34,35)/t19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256046 (US9481672, 227) Show SMILES CN1C(=O)C2(CC2)c2cc(ccc12)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H20F3N3O5/c1-30-20-7-5-13(11-18(20)25(9-10-25)23(30)36)31-12-16(22(34)35)21(33)32(24(31)37)19-8-6-14-15(19)3-2-4-17(14)26(27,28)29/h2-5,7,11-12,19H,6,8-10H2,1H3,(H,34,35)/t19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256059 (US9481672, 241) Show SMILES Cn1c2ccc(cc2n(CC(F)(F)F)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C25H18F6N4O5/c1-32-18-7-5-12(9-19(18)34(22(32)39)11-24(26,27)28)33-10-15(21(37)38)20(36)35(23(33)40)17-8-6-13-14(17)3-2-4-16(13)25(29,30)31/h2-5,7,9-10,17H,6,8,11H2,1H3,(H,37,38)/t17-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256062 (US9481672, 244) Show SMILES CCn1c2cc(ccc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C25H21F3N4O5/c1-3-30-20-11-13(7-9-19(20)29(2)23(30)36)31-12-16(22(34)35)21(33)32(24(31)37)18-10-8-14-15(18)5-4-6-17(14)25(26,27)28/h4-7,9,11-12,18H,3,8,10H2,1-2H3,(H,34,35)/t18-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256066 (US9481672, 248) Show SMILES Cn1c2ccc(cc2n(C2CC2)c1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C26H21F3N4O5/c1-30-20-9-7-14(11-21(20)32(24(30)37)13-5-6-13)31-12-17(23(35)36)22(34)33(25(31)38)19-10-8-15-16(19)3-2-4-18(15)26(27,28)29/h2-4,7,9,11-13,19H,5-6,8,10H2,1H3,(H,35,36)/t19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256083 (US9481672, 265) Show SMILES CCN1C(=O)C(C)(C)c2ccc(cc12)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C25H21ClF3N3O5/c1-4-30-18-10-14(8-9-16(18)24(2,3)22(30)36)31-12-15(21(34)35)20(33)32(23(31)37)11-13-6-5-7-17(19(13)26)25(27,28)29/h5-10,12H,4,11H2,1-3H3,(H,34,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256088 (BDBM256092 | BDBM256093 | US9481672, 270) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(C2CCCc3c(Cl)cccc23)c1=O Show InChI InChI=1S/C24H21ClN4O5/c1-26-19-10-9-13(11-20(19)27(2)23(26)33)28-12-16(22(31)32)21(30)29(24(28)34)18-8-4-5-14-15(18)6-3-7-17(14)25/h3,6-7,9-12,18H,4-5,8H2,1-2H3,(H,31,32)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256095 (US9481672, 277) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(C(O)=O)c(=O)n(C2CCCc3c2cccc3C(F)(F)F)c1=O Show InChI InChI=1S/C25H21F3N4O5/c1-29-19-10-9-13(11-20(19)30(2)23(29)36)31-12-16(22(34)35)21(33)32(24(31)37)18-8-4-5-14-15(18)6-3-7-17(14)25(26,27)28/h3,6-7,9-12,18H,4-5,8H2,1-2H3,(H,34,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256111 (US9481672, 294) Show SMILES Cn1c2ccc(cc2oc1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C24H18F3N3O6/c1-28-18-9-8-12(10-19(18)36-23(28)35)29-11-15(21(32)33)20(31)30(22(29)34)17-7-3-4-13-14(17)5-2-6-16(13)24(25,26)27/h2,5-6,8-11,17H,3-4,7H2,1H3,(H,32,33)/t17-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256116 (US9481672, 300) Show SMILES Cn1c2ccc(cc2sc1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C24H18F3N3O5S/c1-28-18-9-8-12(10-19(18)36-23(28)35)29-11-15(21(32)33)20(31)30(22(29)34)17-7-3-4-13-14(17)5-2-6-16(13)24(25,26)27/h2,5-6,8-11,17H,3-4,7H2,1H3,(H,32,33)/t17-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM192449 (US9187466, 32 | US9687476, 32) Show SMILES OC(=O)c1cccc(Cn2c(nn(Cc3nnc(Cc4c(Cl)cccc4Cl)[nH]3)c2=O)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H19Cl3N6O3/c27-18-9-7-16(8-10-18)24-33-35(26(38)34(24)13-15-3-1-4-17(11-15)25(36)37)14-23-30-22(31-32-23)12-19-20(28)5-2-6-21(19)29/h1-11H,12-14H2,(H,36,37)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9687476 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6QDG
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM88556 (US9695131, 63) Show SMILES Cn1c2ccc(cc2oc1=O)-n1cc(C(=O)NC#N)c(=O)n(C2CCc3c2cccc3C(F)(F)F)c1=O Show InChI InChI=1S/C24H16F3N5O5/c1-30-18-7-5-12(9-19(18)37-23(30)36)31-10-15(20(33)29-11-28)21(34)32(22(31)35)17-8-6-13-14(17)3-2-4-16(13)24(25,26)27/h2-5,7,9-10,17H,6,8H2,1H3,(H,29,33)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9695131 (2017) BindingDB Entry DOI: 10.7270/Q2ZP448Z
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM88378 (US9695131, 15) Show SMILES Cn1c2ccc(cc2sc1=O)-n1cc(-c2nnn[nH]2)c(=O)n(C2CCc3c2cccc3C(F)(F)F)c1=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9695131 (2017) BindingDB Entry DOI: 10.7270/Q2ZP448Z
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM88379 (US9695131, 16 | US9695131, 17 | US9695131, 18) Show SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(-c2nnn[nH]2)c(=O)n(C2CCc3c2cccc3Cl)c1=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9695131 (2017) BindingDB Entry DOI: 10.7270/Q2ZP448Z
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM190338 (US9180120, 42) Show SMILES NC(=O)OC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C23H20ClF6N5O5/c24-13-7-5-12(6-8-13)19-33-35(21(39)34(19)10-17(36)23(28,29)30)11-18(37)32-9-16(40-20(31)38)14-3-1-2-4-15(14)22(25,26)27/h1-8,16-17,36H,9-11H2,(H2,31,38)(H,32,37)/t16?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtitre plates an...				US Patent US9180120 (2015) BindingDB Entry DOI: 10.7270/Q2KK99KH
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255939 (US9481672, 117) Show SMILES CCOC(=O)c1cn(-c2ccc3n(C)c(=O)n(C4CC4)c3c2)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C28H25F3N4O5/c1-3-40-25(37)19-14-33(16-9-11-22-23(13-16)34(15-7-8-15)26(38)32(22)2)27(39)35(24(19)36)21-12-10-17-18(21)5-4-6-20(17)28(29,30)31/h4-6,9,11,13-15,21H,3,7-8,10,12H2,1-2H3/t21-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM255943 (US9481672, 121) Show SMILES Cc1c(Cn2c(=O)c(cn(-c3ccc4n(C)c(=O)n(C)c4c3)c2=O)C(O)=O)cccc1C(F)(F)F Show InChI InChI=1S/C23H19F3N4O5/c1-12-13(5-4-6-16(12)23(24,25)26)10-30-19(31)15(20(32)33)11-29(22(30)35)14-7-8-17-18(9-14)28(3)21(34)27(17)2/h4-9,11H,10H2,1-3H3,(H,32,33)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256011 (US9481672, 189) Show SMILES Cn1c2ccc(cc2oc1=O)-n1cc(C(O)=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O |r| Show InChI InChI=1S/C23H16F3N3O6/c1-27-17-7-5-11(9-18(17)35-22(27)34)28-10-14(20(31)32)19(30)29(21(28)33)16-8-6-12-13(16)3-2-4-15(12)23(24,25)26/h2-5,7,9-10,16H,6,8H2,1H3,(H,31,32)/t16-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256027 (US9481672, 205) Show SMILES CN1C(=O)C(C)(C)c2ccc(cc12)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O Show InChI InChI=1S/C25H22F3N3O5/c1-13-14(6-5-7-17(13)25(26,27)28)11-31-20(32)16(21(33)34)12-30(23(31)36)15-8-9-18-19(10-15)29(4)22(35)24(18,2)3/h5-10,12H,11H2,1-4H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256028 (US9481672, 206) Show SMILES CN1C(=O)C(C)(C)c2ccc(cc12)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C24H19ClF3N3O5/c1-23(2)15-8-7-13(9-17(15)29(3)21(23)35)30-11-14(20(33)34)19(32)31(22(30)36)10-12-5-4-6-16(18(12)25)24(26,27)28/h4-9,11H,10H2,1-3H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256042 (US9481672, 223) Show SMILES CN1C(=O)C(C)(C)c2cc(ccc12)-n1cc(C(O)=O)c(=O)n(C2CCc3c2cccc3C(F)(F)F)c1=O Show InChI InChI=1S/C26H22F3N3O5/c1-25(2)18-11-13(7-9-20(18)30(3)23(25)36)31-12-16(22(34)35)21(33)32(24(31)37)19-10-8-14-15(19)5-4-6-17(14)26(27,28)29/h4-7,9,11-12,19H,8,10H2,1-3H3,(H,34,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256045 (US9481672, 226) Show SMILES CN1C(=O)C2(CC2)c2cc(ccc12)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2C)C(F)(F)F)c1=O Show InChI InChI=1S/C25H20F3N3O5/c1-13-14(4-3-5-17(13)25(26,27)28)11-31-20(32)16(21(33)34)12-30(23(31)36)15-6-7-19-18(10-15)24(8-9-24)22(35)29(19)2/h3-7,10,12H,8-9,11H2,1-2H3,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair
chymase (Mesocricetus auratus (Golden hamster))	BDBM256113 (US9481672, 296) Show SMILES Cn1c2ccc(cc2sc1=O)-n1cc(C(O)=O)c(=O)n(C2CCCc3c2cccc3C(F)(F)F)c1=O Show InChI InChI=1S/C24H18F3N3O5S/c1-28-18-9-8-12(10-19(18)36-23(28)35)29-11-15(21(32)33)20(31)30(22(29)34)17-7-3-4-13-14(17)5-2-6-16(13)24(25,26)27/h2,5-6,8-11,17H,3-4,7H2,1H3,(H,32,33)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...				US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7
					More data for this Ligand-Target Pair

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