| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [30-579] |
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| Ligand | BDBM155358 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 8.2±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 67±n/a nM |
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| Comments | extracted |
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| Citation |  Roughley, S; Walls, S; Hart, T; Parsons, R; Brough, P; Graham, C; Macias, A Azetidine derivatives US Patent US9006269 Publication Date 4/14/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 [30-579] |
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| Name: | Fatty-acid amide hydrolase 1 [30-579] |
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| Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 |
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| Type: | Single-pass membrane protein; homodimer |
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| Mol. Mass.: | 60474.00 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P97612 (aa 30-579) |
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| Residue: | 550 |
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| Sequence: | RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSG
ELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKG
HDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWK
SSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGC
VYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGY
YETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFL
QNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH
EIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPV
TTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE
QLMTPQKQPS
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| BDBM155358 |
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| n/a |
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| Name | BDBM155358 |
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| Synonyms: | US10383871, Example 4 | US10918640, Example 4 | US9006269, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19N3O2 |
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| Mol. Mass. | 345.3945 |
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| SMILES | O=C(Nc1cccnc1)N1CC(C1)Oc1ccc(cc1)-c1ccccc1 |
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| Structure | 
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