| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM155935 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Receptor Assay |
|---|
| pH | 7.4±n/a |
|---|
| IC50 | 8.9±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Zhang, G; Chen, Y; Xu, X; Liu, X; Zhao, S; Liu, B; Yu, M; Qiu, Y Alicyclic[c] benzopyrone derivatives and uses thereof US Patent US9018213 Publication Date 4/28/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 49540.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P19020 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
|
|
|
|---|
| BDBM155935 |
|---|
| n/a |
|---|
| Name | BDBM155935 |
|---|
| Synonyms: | US9018213, 5 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27FN2O4 |
|---|
| Mol. Mass. | 462.5127 |
|---|
| SMILES | Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c4CCCc4c(=O)oc3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
