| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal protective protein |
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| Ligand | BDBM156789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 5.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 99.8±n/a nM |
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| Comments | extracted |
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| Citation |  Ruf, S; Sadowski, T; Wirth, K; Schreuder, H; Buning, C Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals US Patent US9029559 Publication Date 5/12/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysosomal protective protein |
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| Name: | Lysosomal protective protein |
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| Synonyms: | CTSA | Cathepsin A | Cathepsin A (CTSA) | Lysosomal protective protein | PPGB | PPGB_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 54465.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10619 |
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| Residue: | 480 |
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| Sequence: | MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSK
HLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLI
ANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYA
GIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHC
CSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQD
LGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWD
MCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKME
VQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
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| BDBM156789 |
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| n/a |
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| Name | BDBM156789 |
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| Synonyms: | US9029559, 218 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20F2N2O4 |
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| Mol. Mass. | 426.4127 |
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| SMILES | COc1ccc(nc1-c1cc(F)ccc1F)C(=O)N[C@@H](CC(O)=O)c1ccc(C)cc1 |
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| Structure | 
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