| Reaction Details |
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 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
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| Ligand | BDBM165009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Ki | 8.4±n/a nM |
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| Citation |  Chai, W; Deckhut, C; Dvorak, CA; Eccles, W; Edwards, JP; Goldberg, SD; Krawczuk, PJ; Lebsack, AD; Liu, J; Tanis, VM; Tarantino, KT 1,2,5-substituted benzimidazoles as FLAP modulators US Patent US9067917 Publication Date 6/30/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Arachidonate 5-lipoxygenase-activating protein |
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| Name: | Arachidonate 5-lipoxygenase-activating protein |
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| Synonyms: | 5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 18159.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20292 |
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| Residue: | 161 |
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| Sequence: | MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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| BDBM165009 |
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| n/a |
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| Name | BDBM165009 |
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| Synonyms: | US9067917, 44 | US9682971, 44 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H31N3O3 |
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| Mol. Mass. | 505.6068 |
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| SMILES | Cc1ccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@H]2C(O)=O)cc1 |r| |
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| Structure | 
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