Reaction Details | |||
---|---|---|---|
![]() | Report a problem with these data | ||
Target | Maternal embryonic leucine zipper kinase | ||
Ligand | BDBM166122 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assay | ||
pH | 7.4±n/a | ||
Temperature | 298.15±n/a K | ||
IC50 | 1.8±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Maternal embryonic leucine zipper kinase | |||
Name: | Maternal embryonic leucine zipper kinase | ||
Synonyms: | KIAA0175 | MELK | MELK_HUMAN | Maternal embryonic leucine zipper kinase | Maternal embryonic leucine zipper kinase (MELK) | ||
Type: | Enzyme | ||
Mol. Mass.: | 74665.45 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q14680 | ||
Residue: | 651 | ||
Sequence: |
| ||
BDBM166122 | |||
n/a | |||
Name | BDBM166122 | ||
Synonyms: | US9067937, 66 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H22Cl2N4O2 | ||
Mol. Mass. | 445.342 | ||
SMILES | CC(=O)c1cnc2ccc(nc2c1N[C@H]1CC[C@H](N)CC1)-c1cc(Cl)c(O)c(Cl)c1 |r,wU:14.15,wD:17.19,(6.67,-1.71,;5.33,-.94,;5.33,.6,;4,-1.71,;4,-3.25,;2.67,-4.02,;1.33,-3.25,;,-4.02,;-1.33,-3.25,;-1.33,-1.71,;,-.94,;1.33,-1.71,;2.67,-.94,;2.67,.94,;1.33,1.71,;,.94,;-1.33,1.71,;-1.33,3.25,;-2.67,4.02,;,4.02,;1.33,3.25,;-2.67,-.94,;-2.67,.6,;-4,1.37,;-4,2.91,;-5.33,.6,;-6.67,1.37,;-5.33,-.94,;-6.67,-1.71,;-4,-1.71,)| | ||
Structure | ![]() |