Reaction Details | |||
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![]() | Report a problem with these data | ||
Target | Maternal embryonic leucine zipper kinase | ||
Ligand | BDBM166150 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assay | ||
pH | 7.4±n/a | ||
Temperature | 298.15±n/a K | ||
IC50 | 0.6±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Maternal embryonic leucine zipper kinase | |||
Name: | Maternal embryonic leucine zipper kinase | ||
Synonyms: | KIAA0175 | MELK | MELK_HUMAN | Maternal embryonic leucine zipper kinase | Maternal embryonic leucine zipper kinase (MELK) | ||
Type: | Enzyme | ||
Mol. Mass.: | 74665.45 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q14680 | ||
Residue: | 651 | ||
Sequence: |
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BDBM166150 | |||
n/a | |||
Name | BDBM166150 | ||
Synonyms: | US9067937, 94 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H28Cl2N4O2 | ||
Mol. Mass. | 487.421 | ||
SMILES | CN(C)C[C@H]1CC[C@H](CC1)Nc1c(cnc2ccc(nc12)-c1cc(Cl)c(O)c(Cl)c1)C(C)=O |r,wU:7.10,4.3,(-4,5,;-2.67,4.23,;-1.33,5.01,;-2.67,2.69,;-1.33,1.92,;,2.69,;1.33,1.92,;1.33,.38,;,-.38,;-1.33,.38,;2.67,-.39,;2.67,-1.93,;4,-2.7,;4,-4.24,;2.67,-5.01,;1.33,-4.24,;,-5.01,;-1.33,-4.24,;-1.33,-2.7,;,-1.93,;1.33,-2.7,;-2.67,-1.93,;-4,-2.7,;-5.33,-1.93,;-6.67,-2.7,;-5.33,-.39,;-6.67,.38,;-4,.38,;-4,1.92,;-2.67,-.39,;5.33,-1.93,;6.67,-2.7,;5.33,-.39,)| | ||
Structure | ![]() |